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Reading: Amy Schumer Clarifies She Lost 50 Pounds ‘Not to Look Hot’ but ‘to Survive’ a Disease ‘That Can Kill You’
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Live the Gossip > Lifestyle > Amy Schumer Clarifies She Lost 50 Pounds ‘Not to Look Hot’ but ‘to Survive’ a Disease ‘That Can Kill You’
Lifestyle

Amy Schumer Clarifies She Lost 50 Pounds ‘Not to Look Hot’ but ‘to Survive’ a Disease ‘That Can Kill You’

Written by: News Room Last updated: December 2, 2025
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NEED TO KNOW

  • Amy Schumer posted an Instagram Reel on Monday, Dec. 1 where she addressed ongoing comments about her weight loss journey
  • The actress said she’s lost 50 lbs. “to survive” — “not to look hot”
  • She also shared that since her weight loss, she’s been “pain free”

Amy Schumer continues to share how her health impacted her weight loss journey.

On Monday, Dec. 1, Schumer, 44, posted an Instagram Reel filmed by her son Gene, 6, whom she shares with husband Chris Fischer.

The video began with Schumer lounging in bed, and continued with Gene sharing a peek at the family’s home. While the video itself included a tour of various rooms, Schumer added text clarifying “questions” about her weight loss journey.

She began by stating that she doesn’t get Botox or filler, and said despite reports she didn’t lose 30 lbs., she lost 50. “Not to look hot which does feel fun and temporary,” she wrote. “I did it to survive.”

“I had a disease that makes your face extremely puffy that can kill you, but the internet caught it, and the disease has cleared,” she wrote seemingly in reference to her Cushing syndrome diagnosis.

Cushing syndrome is a condition where the body has too much cortisol (the primary stress hormone), per the Mayo Clinic. In addition to developing a rounder face from weight gain, some of the other symptoms include weight gain in the arms and legs, high blood pressure and increased stretch marks.

Amy Schumer Dec. 1, 2025 Instagram Reel.

Amy Schumer/Instagram


“Sorry for whatever feeling it’s giving you that I lost that weight,” Schumer continued. The Trainwreck star reiterated that she’s had plastic surgery “over the years” and uses Mounjaro. “Sorry to anyone that lets down.”

But she said, she’s now “pain free” and “can [play] tag” with Gene.

She also remarked on her perimenopause, which she revealed in February 2024 that she was experiencing alongside her endometriosis diagnosis. “Happy to share if anyone has any questions about how I’m looking or feeling or where I am in my perimenopause process.”

Perimenopause is the transitional period before menopause when levels of estrogen start to decrease, according to the Cleveland Clinic. It often causes menopause-like symptoms, such as hot flashes or irregular periods, and can last for years.

She concluded her caption by referencing speculation about her and her husband’s marriage.

“Whatever ends up happening with Chris has nothing to do with weight loss or autism,” she wrote, referring to her husband’s autism diagnosis. “Fingers crossed we can make it through, he’s the best.”

Never miss a story — sign up for PEOPLE’s free daily newsletter to stay up-to-date on the best of what PEOPLE has to offer​​, from celebrity news to compelling human interest stories.

Amy Schumer and Chris Fischer on June 11, 2025 in New York City.

Jamie McCarthy/Getty


PEOPLE reported in November that a source said Schumer and Fischer, 45, remain committed to their relationship amid speculation about their marriage.

“They’re privately working through normal issues that couples in long-term marriages have,” a source exclusively told PEOPLE. “They are both committed to the relationship.”

The recent Instagram Reel isn’t Schumer’s first response to speculation about her marriage to Fischer. In a Nov. 6 Instagram Story, she shared a picture of New York City and praised Hulu’s new series All’s Fair. “And Chris and I are still married,” she added in the caption.

She’s also responded to comments about her weight loss journey. In October, she shared via Instagram how she’s “feeling strong” and like herself. “I’m enjoying how I look, but man it is all about how you feel,” she wrote in the since-deleted Instagram carousel.



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